CNOT7P2

Across TCGA pan-cancer cohorts, CNOT7P2 RNA is linked to patient survival in 16 of 34 cancer types, making it the most broadly survival-associated CNOT7P2 data layer.

The strongest signal is observed in mesothelioma (MESO), where higher CNOT7P2 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated CNOT7P2 expression acts as an unfavorable survival marker, although some lineages such as THCA and UCS show a favorable association.

MESO, DLBC, and ACC are the cancer types where CNOT7P2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	OS	Tertile	IV	0.036	0.602	<.001	72	view →
DLBC	DFS	Tertile	II,III,IV	0.065	0.829	<.001	59	view →
ACC	OS	Tertile	All	0.608	0.907	.004	39	view →
LUSC	OS	Tertile	IV	0.001	0.673	.014	39	view →
TGCT	DFS	Tertile	II,III,IV	0.015	0.919	<.001	36	view →
GBM	OS	Median	All	0.359	0.456	.012	21	view →
THCA	OS	Tertile	All	0.994	0.885	.004	21	view →
PAAD	DFS	Tertile	III,IV	0.118	0.734	.014	18	view →
UCS	DFS	Tertile	II,III,IV	0.831	0.373	.035	18	view →
KICH	DFS	Tertile	III,IV	0.035	0.772	.021	18	view →
LUAD	DFS	Tertile	All	0.852	0.655	.028	12	view →
SKCM	OS	Tertile	IV	0.415	0.861	.014	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 16 lineages.

CNOT7P2–MESO (OS)

Open the MESO breakdown →