CNOT7P1

Across TCGA pan-cancer cohorts, CNOT7P1 RNA is linked to patient survival in 18 of 34 cancer types, making it the most broadly survival-associated CNOT7P1 data layer.

The strongest signal is observed in skin cutaneous melanoma (SKCM), where higher CNOT7P1 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated CNOT7P1 expression acts as an unfavorable survival marker, although some lineages such as SKCM and OV show a favorable association.

SKCM, STAD, and KIRP are the cancer types where CNOT7P1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SKCM	DFS	Median	III,IV	0.363	0.177	<.001	62	view →
STAD	DFS	Median	II,III,IV	0.391	0.652	.001	34	view →
KIRP	DFS	Quartile	All	0.568	0.759	.004	32	view →
OV	OS	Quartile	IV	0.683	0.334	.004	20	view →
KIRC	DFS	Quartile	IV	0.162	0.439	.006	19	view →
CHOL	OS	Tertile	III,IV	0.275	0.886	.045	18	view →
PAAD	OS	Tertile	All	0.605	0.432	.018	13	view →
LUSC	OS	Median	II,III,IV	0.472	0.348	.023	7	view →
MESO	OS	Quartile	All	0.162	0.591	.009	6	view →
TGCT	DFS	Median	II,III,IV	0.750	0.996	.046	6	view →
LIHC	DFS	Tertile	All	0.452	0.565	.021	6	view →
SARC	OS	Quartile	All	0.722	0.864	.009	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 18 lineages.

CNOT7P1–SKCM (DFS)

Open the SKCM breakdown →