Across TCGA patient cohorts, CNOT7 mutation is significantly associated with the total protein of many other genes, with 37 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CNOT7-associated genes across cancer lineages are INPP4B, PCNA, and PKC-b-II_pS660. Each is linked with CNOT7 in more than 1 cancer types. Because this analysis shows association rather than direction, both CNOT7-to-partner and partner-to-CNOT7 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CNOT7→partner) and Y-score (partner→CNOT7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	INPP4B →	-0.438	-3.000	.017	.034	3	2
COAD	PCNA →	+0.410	+2.820	<.001	.035	3	2
COAD	PKC-b-II_pS660 →	-0.404	-3.161	.020	.019	3	2
UCEC	4E-BP1 →	+0.368	+3.489	.001	.002	3	2
UCEC	eEF2 →	+0.376	+3.169	.013	.018	3	2
UCEC	MEK1 →	+0.527	+3.584	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 37 associations by consensus.

Exploration

CNOT7 survival (RNA) · tumor vs normal (RNA) · all CNOT7 data types