Across TCGA cell cohorts, CNOT7 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,871 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CNOT7-associated GO terms across cancer lineages are Regulation of regulatory ncRNA-mediated heterochromatin formation, Negative regulation of regulatory ncRNA-mediated heterochromatin formation, and piRNA-mediated gene silencing by mRNA destabilization. Each is linked with CNOT7 in more than 17 cancer types. Because this analysis shows association rather than direction, both CNOT7-to-partner and partner-to-CNOT7 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CNOT7→partner) and Y-score (partner→CNOT7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Regulation of regulatory ncRNA-mediated heterochromatin formation →	+0.151	+0.730	<.001	<.001	3	18
PANCREAS	Negative regulation of regulatory ncRNA-mediated heterochromatin formation →	+0.151	+0.730	<.001	<.001	3	18
LIVER	piRNA-mediated gene silencing by mRNA destabilization →	+0.304	+1.125	.004	.004	3	17
STOMACH	Negative regulation of sister chromatid cohesion →	+0.158	+0.910	.001	.002	3	16
SKIN	Positive regulation of telomere capping →	+0.123	+0.692	<.001	<.001	3	15
LIVER	Negative regulation of heterochromatin organization →	+0.147	+1.108	.002	.004	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,871 associations by consensus.

Exploration

CNOT7 survival (RNA) · tumor vs normal (RNA) · all CNOT7 data types