CNOT6L

Across TCGA patient cohorts, CNOT6L RNA expression is significantly associated with the protein abundance of many other proteins, with 12,420 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible CNOT6L-associated proteins across cancer lineages are CGGBP1, ERO1A, and PPP1R12C. Each is linked with CNOT6L in more than 4 cancer types. Because this analysis shows association rather than direction, both CNOT6L-to-partner and partner-to-CNOT6L results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CNOT6L versus CGGBP1 in HNSC, with a Pearson correlation of 0.27.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CNOT6L→partner) and Y-score (partner→CNOT6L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	CGGBP1 →	+0.345	+0.496	<.001	.005	3	5
GBM	ERO1A →	-0.586	-0.298	<.001	.004	3	5
HNSC	PPP1R12C →	+0.237	+0.468	<.001	<.001	3	5
HNSC	RPL3 →	-0.289	-0.497	<.001	<.001	3	5
GBM	RPL7 →	-0.498	-0.378	<.001	<.001	3	5
HNSC	PHF1 →	+0.255	+0.468	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,420 associations by consensus.

CNOT6L vs CGGBP1 — HNSC

Explore this scatter interactively →