CNOT6

Across TCGA patient cohorts, CNOT6 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,615 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CNOT6-associated proteins across cancer lineages are FAF2, SMARCC2_T322, and RFC2. Each is linked with CNOT6 in more than 4 cancer types. Because this analysis shows association rather than direction, both CNOT6-to-partner and partner-to-CNOT6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CNOT6 versus FAF2 in LUAD, with a Pearson correlation of 0.58.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CNOT6→partner) and Y-score (partner→CNOT6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	FAF2 →	+0.272	+0.487	<.001	<.001	3	5
LUAD	SMARCC2_T322 →	+1.057	+0.468	<.001	<.001	3	4
PDAC	RFC2 →	+0.344	+0.449	<.001	<.001	3	4
LSCC	RIF1_S782 →	+0.812	+0.536	<.001	<.001	3	4
GBM	SRSF3 →	+0.415	+0.692	<.001	<.001	3	4
GBM	RBM22 →	+0.365	+0.571	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,615 associations by consensus.

CNOT6 vs FAF2 — LUAD

Explore this scatter interactively →