CNOT3

Across TCGA patient cohorts, CNOT3 RNA expression is significantly associated with the RNA expression of many other genes, with 20,382 significant associations in total. ACC shows the largest number of these associations.

The most reproducible CNOT3-associated genes across cancer lineages are ACIN1, PPP6R1, and ZBTB45. Each is linked with CNOT3 in more than 33 cancer types. Because this analysis shows association rather than direction, both CNOT3-to-partner and partner-to-CNOT3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CNOT3 versus ACIN1 in SCLC, with a Pearson correlation of 0.51.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CNOT3→partner) and Y-score (partner→CNOT3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SCLC	ACIN1 →	+1.580	+0.805	<.001	<.001	3	34
ACC	PPP6R1 →	+1.283	+1.004	<.001	<.001	3	34
ACC	ZBTB45 →	+0.858	+0.971	<.001	<.001	3	34
ACC	YLPM1 →	+1.094	+0.938	<.001	<.001	3	34
DLBC	KDM3B →	+1.376	+0.888	<.001	<.001	3	34
DLBC	CNOT1 →	+1.591	+0.888	<.001	<.001	3	34

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,382 associations by consensus.

CNOT3 vs ACIN1 — SCLC

Explore this scatter interactively →