CNOT3

Across TCGA cell cohorts, CNOT3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,285 significant associations in total. BONE shows the largest number of these associations.

The most reproducible CNOT3-associated GO terms across cancer lineages are Regulation of chromatin organization, mRNA transport, and mRNA alternative polyadenylation. Each is linked with CNOT3 in more than 16 cancer types. Because this analysis shows association rather than direction, both CNOT3-to-partner and partner-to-CNOT3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of chromatin organization grouped by CNOT3-low versus CNOT3-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CNOT3→partner) and Y-score (partner→CNOT3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Regulation of chromatin organization →	+0.103	+0.932	.006	.009	3	17
BONE	mRNA transport →	+0.102	+0.562	<.001	<.001	3	17
LARGE_INTESTINE	mRNA alternative polyadenylation →	+0.091	+0.878	<.001	<.001	3	16
OESOPHAGUS	Positive regulation of gene expression, epigenetic →	+0.083	+0.653	.003	.002	3	15
LUNG_SCLC	P-body assembly →	+0.114	+0.543	.002	.004	2	16
BONE	mRNA export from nucleus →	+0.109	+0.562	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,285 associations by consensus.

Regulation of chromatin organization by CNOT3 expression — STOMACH

Explore this box plot interactively →