CNOT2

Across TCGA patient cohorts, CNOT2 protein abundance is significantly associated with the protein abundance of many other proteins, with 18,887 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CNOT2-associated proteins across cancer lineages are CNOT1, CNOT10, and CNOT3. Each is linked with CNOT2 in more than 8 cancer types. Because this analysis shows association rather than direction, both CNOT2-to-partner and partner-to-CNOT2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CNOT2 versus CNOT1 in GBM, with a Pearson correlation of 0.71.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CNOT2→partner) and Y-score (partner→CNOT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CNOT1 →	+0.229	+0.302	<.001	<.001	3	9
GBM	CNOT10 →	+0.224	+0.332	<.001	<.001	3	7
OV	CNOT3 →	+0.317	+0.330	<.001	<.001	3	7
GBM	CNOT9 →	+0.223	+0.264	<.001	<.001	3	6
UCEC	ATXN2L →	+0.244	+0.140	<.001	<.001	3	5
GBM	ADNP →	+0.316	+0.273	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,887 associations by consensus.

CNOT2 vs CNOT1 — GBM

Explore this scatter interactively →