CNOT11

Across TCGA patient cohorts, CNOT11 RNA expression is significantly associated with the RNA expression of many other genes, with 19,917 significant associations in total. ACC shows the largest number of these associations.

The most reproducible CNOT11-associated genes across cancer lineages are DDX21, MRPL30, and IWS1. Each is linked with CNOT11 in more than 33 cancer types. Because this analysis shows association rather than direction, both CNOT11-to-partner and partner-to-CNOT11 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CNOT11 versus DDX21 in DLBC, with a Pearson correlation of 0.56.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CNOT11→partner) and Y-score (partner→CNOT11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
DLBC	DDX21 →	+1.365	+0.407	<.001	<.001	3	34
ACC	MRPL30 →	+1.018	+1.069	<.001	<.001	3	34
ACC	IWS1 →	+1.133	+1.102	<.001	<.001	3	34
UVM	WDR43 →	+1.293	+0.598	<.001	<.001	3	34
UVM	PRPF40A →	+1.096	+0.562	<.001	<.001	3	34
ACC	CD2AP →	+1.161	+1.222	<.001	<.001	3	34

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,917 associations by consensus.

CNOT11 vs DDX21 — DLBC

Explore this scatter interactively →