CNOT11

Across TCGA patient cohorts, CNOT11 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,947 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CNOT11-associated proteins across cancer lineages are ADAR, CCAR1, and DHX9. Each is linked with CNOT11 in more than 4 cancer types. Because this analysis shows association rather than direction, both CNOT11-to-partner and partner-to-CNOT11 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CNOT11 versus ADAR in LSCC, with a Pearson correlation of 0.50.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CNOT11→partner) and Y-score (partner→CNOT11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ADAR →	+0.320	+0.428	<.001	<.001	3	5
GBM	CCAR1 →	+0.183	+0.225	.005	.003	3	5
LSCC	DHX9 →	+0.298	+0.578	<.001	<.001	3	5
LSCC	SMARCA5 →	+0.304	+0.482	<.001	<.001	3	5
COAD	STAG2 →	+0.220	+0.370	<.001	<.001	3	5
PDAC	TSN →	+0.266	+0.221	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,947 associations by consensus.

CNOT11 vs ADAR — LSCC

Explore this scatter interactively →