CNOT11

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CNOT11 protein abundance is significantly associated with the protein abundance of many other proteins, with 26,571 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CNOT11-associated proteins across cancer lineages are CNOT1, CNOT10, and SF3B1. Each is linked with CNOT11 in more than 9 cancer types. Because this analysis shows association rather than direction, both CNOT11-to-partner and partner-to-CNOT11 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CNOT11 versus CNOT1 in GBM, with a Pearson correlation of 0.71.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CNOT11→partner) and Y-score (partner→CNOT11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMCNOT1 →+0.219+0.227<.001<.001310
PDACCNOT10 →+0.241+0.286<.001<.00139
OVSF3B1 →+0.235+0.245<.001<.00139
OVLUM →-0.882-0.229<.001<.00139
BRCAOLFML3 →-0.931-0.279<.001<.00139
OVPRKG1 →-0.841-0.292<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 26,571 associations by consensus.

CNOT11 vs CNOT1 — GBM

Per-sample scatter of CNOT11 vs CNOT1 in GBM (Pearson r = 0.71).

Explore this scatter interactively →

Exploration