CNOT11

Across TCGA cell cohorts, CNOT11 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,162 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CNOT11-associated GO terms across cancer lineages are Phospholipid biosynthetic process, Glycerolipid biosynthetic process, and Symbiont-mediated disruption of host cell PML body. Each is linked with CNOT11 in more than 11 cancer types. Because this analysis shows association rather than direction, both CNOT11-to-partner and partner-to-CNOT11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Phospholipid biosynthetic process grouped by CNOT11-low versus CNOT11-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CNOT11→partner) and Y-score (partner→CNOT11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Phospholipid biosynthetic process →	+0.045	+0.763	.001	<.001	3	12
STOMACH	Glycerolipid biosynthetic process →	+0.041	+0.784	.004	.001	3	11
UPPER_AERODIGESTIVE_TRACT	Symbiont-mediated disruption of host cell PML body →	+0.087	+0.567	.001	.005	3	11
STOMACH	Glycerophospholipid biosynthetic process →	+0.047	+0.759	.001	<.001	3	10
LUNG_NSCLC_LUAD	Copper ion export →	-0.148	-0.511	<.001	.001	3	10
SOFT_TISSUE	Regulation of centrosome duplication →	+0.060	+0.569	.006	.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,162 associations by consensus.

Phospholipid biosynthetic process by CNOT11 expression — STOMACH

Explore this box plot interactively →