CNOT10

Across TCGA patient cohorts, CNOT10 protein abundance is significantly associated with the RNA expression of many other genes, with 9,769 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CNOT10-associated genes across cancer lineages are FOLR2, EZH2, and GINS2. Each is linked with CNOT10 in more than 5 cancer types. Because this analysis shows association rather than direction, both CNOT10-to-partner and partner-to-CNOT10 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CNOT10 versus FOLR2 in GBM, with a Pearson correlation of -0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CNOT10→partner) and Y-score (partner→CNOT10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	FOLR2 →	-1.169	-0.178	.001	.001	3	6
GBM	EZH2 →	+0.861	+0.176	<.001	<.001	3	5
LUAD	GINS2 →	+1.077	+0.140	<.001	<.001	3	5
GBM	VSIG4 →	-1.457	-0.193	<.001	<.001	3	5
HNSC	H2BC5 →	+1.054	+0.144	.007	.001	3	5
GBM	KIF15 →	+1.215	+0.214	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,769 associations by consensus.

CNOT10 vs FOLR2 — GBM

Explore this scatter interactively →