CNNM3

Across TCGA cell cohorts, CNNM3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,633 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CNNM3-associated GO terms across cancer lineages are Magnesium ion homeostasis, Transcription pausing by RNA polymerase II, and Positive regulation of DNA repair. Each is linked with CNNM3 in more than 14 cancer types. Because this analysis shows association rather than direction, both CNNM3-to-partner and partner-to-CNNM3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Magnesium ion homeostasis grouped by CNNM3-low versus CNNM3-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CNNM3→partner) and Y-score (partner→CNNM3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Magnesium ion homeostasis →	+0.148	+1.286	<.001	<.001	3	15
BONE	Transcription pausing by RNA polymerase II →	+0.173	+0.888	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Positive regulation of DNA repair →	+0.086	+1.096	<.001	<.001	3	14
OESOPHAGUS	Phospholipid biosynthetic process →	+0.062	+1.024	<.001	.001	3	13
UPPER_AERODIGESTIVE_TRACT	Regulation of chromatin organization →	+0.073	+0.717	<.001	<.001	3	13
BONE	Late viral transcription →	+0.172	+1.066	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,633 associations by consensus.

Magnesium ion homeostasis by CNNM3 expression — OESOPHAGUS

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