CNNM2

Across TCGA patient cohorts, CNNM2 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,298 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CNNM2-associated proteins across cancer lineages are PHC3, RPL5, and RPS6. Each is linked with CNNM2 in more than 4 cancer types. Because this analysis shows association rather than direction, both CNNM2-to-partner and partner-to-CNNM2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CNNM2 versus PHC3 in BRCA, with a Pearson correlation of 0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CNNM2→partner) and Y-score (partner→CNNM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	PHC3 →	+0.425	+0.444	<.001	<.001	3	5
GBM	RPL5 →	-0.279	-0.478	<.001	<.001	3	5
GBM	RPS6 →	-0.389	-0.316	<.001	<.001	3	5
HNSC	SMC3 →	+0.269	+0.434	<.001	<.001	3	5
GBM	GFPT2 →	-0.643	-0.358	<.001	<.001	3	5
CCRCC	GFPT2_T227 →	-2.056	-0.516	.001	.005	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,298 associations by consensus.

CNNM2 vs PHC3 — BRCA

Explore this scatter interactively →