CNNM2

Across TCGA patient cohorts, CNNM2 protein abundance is significantly associated with the RNA expression of many other genes, with 4,136 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CNNM2-associated genes across cancer lineages are DNAJC6, STOX1, and SH3GL2. Each is linked with CNNM2 in more than 2 cancer types. Because this analysis shows association rather than direction, both CNNM2-to-partner and partner-to-CNNM2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CNNM2 versus DNAJC6 in LUAD, with a Pearson correlation of 0.59.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CNNM2→partner) and Y-score (partner→CNNM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	DNAJC6 →	+1.356	+1.494	<.001	.001	3	3
UCEC	STOX1 →	+1.257	+0.923	.003	.001	3	3
GBM	SH3GL2 →	+1.378	+0.300	<.001	<.001	3	2
GBM	ENPP6 →	+0.992	+0.356	.002	.002	3	2
COAD	TMIGD2 →	+1.362	+0.648	<.001	.005	3	2
GBM	KCNN1 →	+1.095	+0.446	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,136 associations by consensus.

CNNM2 vs DNAJC6 — LUAD

Explore this scatter interactively →