CNNM2

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, CNNM2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,370 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CNNM2-associated GO terms across cancer lineages are Viral translational termination-reinitiation, Glycerolipid biosynthetic process, and Magnesium ion homeostasis. Each is linked with CNNM2 in more than 15 cancer types. Because this analysis shows association rather than direction, both CNNM2-to-partner and partner-to-CNNM2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Viral translational termination-reinitiation grouped by CNNM2-low versus CNNM2-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CNNM2→partner) and Y-score (partner→CNNM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKINViral translational termination-reinitiation →+0.093+0.617<.001<.001316
OESOPHAGUSGlycerolipid biosynthetic process →+0.048+0.625<.001.001315
LUNG_NSCLC_LUSCMagnesium ion homeostasis →+0.148+0.900.002.003314
UPPER_AERODIGESTIVE_TRACTRegulation of autophagosome maturation →+0.088+0.639<.001.001314
BREASTRetrograde transport, endosome to Golgi →+0.074+0.584.001.004314
OESOPHAGUSCytosolic transport →+0.087+0.818<.001<.001313
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,370 associations by consensus.

Viral translational termination-reinitiation by CNNM2 expression — SKIN

Box plot of Viral translational termination-reinitiation in CNNM2-low vs CNNM2-high samples in SKIN.

Explore this box plot interactively →

Exploration