Across TCGA pan-cancer cohorts, CNN3P1 RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of CNN3P1’s most consistent transcriptional readouts.
The strongest signal is observed in thyroid carcinoma (THCA), where CNN3P1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types CNN3P1 is over-expressed in tumor.
THCA are the cancer types where CNN3P1 tumor–normal differential expression is most reproducible.