CNN3

Across TCGA cell cohorts, CNN3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,622 significant associations in total. BONE shows the largest number of these associations.

The most reproducible CNN3-associated GO terms across cancer lineages are Positive regulation of cytoskeleton organization, Regulation of hippo signaling, and Cell division. Each is linked with CNN3 in more than 14 cancer types. Because this analysis shows association rather than direction, both CNN3-to-partner and partner-to-CNN3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of cytoskeleton organization grouped by CNN3-low versus CNN3-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CNN3→partner) and Y-score (partner→CNN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Positive regulation of cytoskeleton organization →	+0.127	+2.320	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Regulation of hippo signaling →	+0.076	+1.441	.001	.002	3	14
KIDNEY	Cell division →	+0.065	+1.335	<.001	.001	3	13
KIDNEY	Regulation of protein K48-linked ubiquitination →	+0.129	+1.180	<.001	<.001	3	13
BREAST	Spindle elongation →	+0.188	+1.758	<.001	<.001	3	12
LUNG_NSCLC_LUSC	Peptidyl-lysine oxidation →	+1.487	+4.054	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,622 associations by consensus.

Positive regulation of cytoskeleton organization by CNN3 expression — BONE

Explore this box plot interactively →