CNN2P4

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, CNN2P4 RNA is linked to patient survival in 13 of 34 cancer types, making it the most broadly survival-associated CNN2P4 data layer.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher CNN2P4 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated CNN2P4 expression acts as an unfavorable survival marker, although some lineages such as UCEC and ESCA show a favorable association.

UCEC, LIHC, and THYM are the cancer types where CNN2P4 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
UCECDFSMedianAll0.7250.531<.00196view →
LIHCDFSTertileIII,IV0.2020.420.00633view →
THYMDFSTertileII,III,IV0.7870.990.02027view →
MESOOSQuartileII,III,IV0.2430.433.01420view →
ACCOSTertileIII,IV0.2280.628.00318view →
TGCTDFSTertileII,III,IV0.6210.949.03418view →
THCADFSTertileIV0.6061.000<.00113view →
ESCADFSTertileIII,IV0.5610.317.03112view →
LUSCDFSTertileAll0.7330.631.01210view →
CHOLDFSTertileIV0.9500.406.0409view →
COADOSMedianIV0.3570.784.0426view →
OVOSTertileAll0.2520.343.0414view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 13 lineages.

Exploration