CNN2P3

Across TCGA pan-cancer cohorts, CNN2P3 RNA is linked to patient survival in 12 of 34 cancer types, making it the most broadly survival-associated CNN2P3 data layer.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher CNN2P3 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated CNN2P3 expression acts as an unfavorable survival marker, although some lineages such as ESCA and OV show a favorable association.

KIRP, KICH, and BLCA are the cancer types where CNN2P3 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	OS	Tertile	All	0.763	0.923	<.001	67	view →
KICH	DFS	Tertile	All	0.043	0.971	<.001	54	view →
BLCA	DFS	Tertile	III,IV	0.149	0.340	.007	45	view →
UVM	DFS	Tertile	All	0.079	0.746	<.001	27	view →
LUAD	DFS	Tertile	IV	0.223	0.710	.043	18	view →
MESO	OS	Tertile	IV	0.077	0.592	.019	18	view →
ESCA	DFS	Tertile	IV	0.704	0.271	.017	12	view →
CHOL	OS	Tertile	All	0.184	0.640	.012	9	view →
SARC	OS	Tertile	All	0.718	0.836	.026	3	view →
OV	OS	Median	IV	0.693	0.560	.035	2	view →
STAD	DFS	Tertile	II,III,IV	0.565	0.675	.029	1	view →
LGG	DFS	Tertile	All	0.381	0.519	.031	1	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 12 lineages.

CNN2P3–KIRP (OS)

Open the KIRP breakdown →