CNN2

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, CNN2 mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. URINARY_TRACT shows the largest number of these associations.

The most reproducible CNN2-associated genes across cancer lineages are PRKACG. Each is linked with CNN2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CNN2-to-partner and partner-to-CNN2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PRKACG grouped by CNN2-low versus CNN2-high in URINARY_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CNN2→partner) and Y-score (partner→CNN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
URINARY_TRACTPRKACG →+0.006+5.087<.001.00431
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

PRKACG by CNN2 expression — URINARY_TRACT

Box plot of PRKACG in CNN2-low vs CNN2-high samples in URINARY_TRACT.

Explore this box plot interactively →

Exploration