CNN1

Across TCGA cell cohorts, CNN1 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CNN1-associated genes across cancer lineages are IL20 and EDDM3A. Each is linked with CNN1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CNN1-to-partner and partner-to-CNN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IL20 grouped by CNN1-low versus CNN1-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CNN1→partner) and Y-score (partner→CNN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	IL20 →	+0.030	+4.705	.006	.003	3	1
BLOOD_Leukemia	EDDM3A →	+0.027	+4.409	.008	.005	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

IL20 by CNN1 expression — BLOOD_Leukemia

Explore this box plot interactively →