CNMD

Across TCGA pan-cancer cohorts, CNMD mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated CNMD data layer compared with 21 for mass-spec protein and 7 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher CNMD mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated CNMD expression acts as an unfavorable survival marker.

LUAD, LSCC, and HNSC are the cancer types where CNMD mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Median	III,IV	0.508	0.916	.006	9	view →
LSCC	DFS	Tertile	All	0.701	0.883	.027	7	view →
HNSC	DFS	Median	All	0.891	1.000	.021	4	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

CNMD–LUAD (DFS)

Open the LUAD breakdown →