CNKSR2

Across TCGA patient cohorts, CNKSR2 RNA expression is significantly associated with the RNA expression of many other genes, with 17,381 significant associations in total. UVM shows the largest number of these associations.

The most reproducible CNKSR2-associated genes across cancer lineages are KLHL34, SETBP1, and CPLANE1. Each is linked with CNKSR2 in more than 27 cancer types. Because this analysis shows association rather than direction, both CNKSR2-to-partner and partner-to-CNKSR2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CNKSR2 versus KLHL34 in PCPG, with a Pearson correlation of 0.65.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CNKSR2→partner) and Y-score (partner→CNKSR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PCPG	KLHL34 →	+0.966	+1.117	<.001	<.001	3	28
STAD	SETBP1 →	+1.470	+0.816	<.001	<.001	3	27
UVM	CPLANE1 →	+1.193	+0.313	<.001	<.001	3	27
UVM	ZYG11B →	+1.185	+0.360	<.001	.004	2	28
UVM	SCAI →	+0.705	+0.368	<.001	.005	2	28
UVM	ZC2HC1A →	+1.729	+0.255	<.001	<.001	3	27

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,381 associations by consensus.

CNKSR2 vs KLHL34 — PCPG

Explore this scatter interactively →