CNKSR2

Across TCGA patient cohorts, CNKSR2 RNA expression is significantly associated with the protein abundance of many other proteins, with 19,852 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CNKSR2-associated proteins across cancer lineages are RTN1, CNKSR2_S908, and SARM1. Each is linked with CNKSR2 in more than 6 cancer types. Because this analysis shows association rather than direction, both CNKSR2-to-partner and partner-to-CNKSR2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CNKSR2 versus RTN1 in UCEC, with a Pearson correlation of 0.32.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CNKSR2→partner) and Y-score (partner→CNKSR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RTN1 →	+0.442	+0.646	<.001	.002	3	7
LSCC	CNKSR2_S908 →	+1.701	+0.645	<.001	<.001	3	7
COAD	SARM1 →	+0.471	+0.054	<.001	<.001	3	7
HNSC	AGO1 →	+0.380	+0.635	<.001	<.001	3	6
HNSC	HDGFL3 →	+0.639	+0.510	<.001	<.001	3	6
HNSC	PLAC9 →	+1.090	+0.360	<.001	.009	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,852 associations by consensus.

CNKSR2 vs RTN1 — UCEC

Explore this scatter interactively →