CNKSR2

Across TCGA patient cohorts, CNKSR2 protein abundance is significantly associated with the RNA expression of many other genes, with 3,858 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CNKSR2-associated genes across cancer lineages are PRKCG, ANKRD18CP, and SCG5. Each is linked with CNKSR2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CNKSR2-to-partner and partner-to-CNKSR2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CNKSR2 versus PRKCG in GBM, with a Pearson correlation of 0.69.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CNKSR2→partner) and Y-score (partner→CNKSR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PRKCG →	+0.766	+0.454	<.001	<.001	3	2
LSCC	ANKRD18CP →	+0.774	+0.421	.003	.004	3	2
LSCC	SCG5 →	+1.275	+0.412	.005	.006	3	2
LSCC	COX6CP10 →	+1.122	+0.401	<.001	.004	3	2
LSCC	KCNAB1-AS1 →	+0.358	+0.441	.001	.002	3	2
LSCC	CYFIP2 →	+1.412	+0.395	.002	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,858 associations by consensus.

CNKSR2 vs PRKCG — GBM

Explore this scatter interactively →