CNKSR2

Across TCGA cell cohorts, CNKSR2 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,760 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible CNKSR2-associated GO terms across cancer lineages are Positive regulation of double-strand break repair via homologous recombination, Chromosome condensation, and Regulation of protein localization to Cajal body. Each is linked with CNKSR2 in more than 8 cancer types. Because this analysis shows association rather than direction, both CNKSR2-to-partner and partner-to-CNKSR2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of double-strand break repair via homologous recombination grouped by CNKSR2-low versus CNKSR2-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CNKSR2→partner) and Y-score (partner→CNKSR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Positive regulation of double-strand break repair via homologous recombination →	+0.082	+0.705	<.001	<.001	3	9
SKIN	Chromosome condensation →	+0.132	+0.859	<.001	<.001	3	9
SKIN	Regulation of protein localization to Cajal body →	+0.072	+1.011	<.001	<.001	3	9
SKIN	Positive regulation of protein localization to Cajal body →	+0.072	+1.011	<.001	<.001	3	9
SKIN	Chromosome segregation →	+0.069	+0.725	.002	.002	3	9
SKIN	Nuclear division →	+0.053	+0.770	.003	.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,760 associations by consensus.

Positive regulation of double-strand break repair via homologous recombination by CNKSR2 expression — OVARY

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