CNIH1

Across TCGA patient cohorts, CNIH1 protein abundance is significantly associated with the RNA expression of many other genes, with 1,262 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible CNIH1-associated genes across cancer lineages are CDKN3, KPNA2, and GPR21. Each is linked with CNIH1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CNIH1-to-partner and partner-to-CNIH1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CNIH1 versus CDKN3 in LUAD, with a Pearson correlation of 0.97.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CNIH1→partner) and Y-score (partner→CNIH1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	CDKN3 →	+2.012	+0.722	<.001	.002	3	2
LUAD	KPNA2 →	+1.582	+0.722	.003	.002	3	2
PDAC	GPR21 →	+0.640	+0.863	.002	.009	3	2
GBM	RNU6-686P →	+1.426	+0.723	.004	.001	3	2
LUAD	CENPM →	+1.322	+0.722	.006	.002	2	2
LUAD	PRMT5 →	+0.925	+0.722	.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,262 associations by consensus.

CNIH1 vs CDKN3 — LUAD

Explore this scatter interactively →