CNIH1

Across TCGA cell cohorts, CNIH1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,286 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible CNIH1-associated GO terms across cancer lineages are Protein catabolic process at synapse, Protein catabolic process at postsynapse, and Protein localization to condensed chromosome. Each is linked with CNIH1 in more than 9 cancer types. Because this analysis shows association rather than direction, both CNIH1-to-partner and partner-to-CNIH1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein catabolic process at synapse grouped by CNIH1-low versus CNIH1-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CNIH1→partner) and Y-score (partner→CNIH1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Protein catabolic process at synapse →	+0.134	+0.694	.001	.001	3	10
URINARY_TRACT	Protein catabolic process at postsynapse →	+0.134	+0.694	.001	.001	3	10
OESOPHAGUS	Protein localization to condensed chromosome →	+0.199	+0.872	<.001	.001	3	10
SKIN	Monoubiquitinated protein deubiquitination →	+0.107	+0.783	.001	<.001	3	9
SOFT_TISSUE	tRNA C3-cytosine methylation →	+0.113	+0.849	<.001	<.001	3	9
BREAST	Vesicle tethering to Golgi →	+0.091	+0.845	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,286 associations by consensus.

Protein catabolic process at synapse by CNIH1 expression — URINARY_TRACT

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