CNGB3

Across TCGA cell cohorts, CNGB3 RNA expression is significantly associated with the go_rna of many other GO terms, with 808 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible CNGB3-associated GO terms across cancer lineages are Iron coordination entity transport, Regulation of natural killer cell differentiation, and Membrane fission. Each is linked with CNGB3 in more than 4 cancer types. Because this analysis shows association rather than direction, both CNGB3-to-partner and partner-to-CNGB3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Iron coordination entity transport grouped by CNGB3-low versus CNGB3-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CNGB3→partner) and Y-score (partner→CNGB3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Iron coordination entity transport →	+0.131	+0.342	.001	.008	3	5
PANCREAS	Regulation of natural killer cell differentiation →	-0.353	-0.116	<.001	.003	3	5
UPPER_AERODIGESTIVE_TRACT	Membrane fission →	+0.074	+0.180	<.001	.002	3	5
URINARY_TRACT	Positive regulation of viral genome replication →	+0.077	+0.243	.001	.006	3	5
LUNG_NSCLC_LUSC	Cell surface receptor signaling pathway via STAT →	-0.061	-0.223	.002	.003	3	4
SKIN	Chromosomal 5-methylcytosine DNA demethylation pathway →	+0.080	+0.046	.002	.007	2	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 808 associations by consensus.

Iron coordination entity transport by CNGB3 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →