CNGA4

Across TCGA pan-cancer cohorts, CNGA4 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated CNGA4 data layer compared with 23 for mass-spec protein and 7 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher CNGA4 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated CNGA4 expression acts as an unfavorable survival marker, although some lineages such as CCRCC show a favorable association.

CCRCC, LUAD, and GBM are the cancer types where CNGA4 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Tertile	II,III,IV	0.880	0.341	.049	12	view →
LUAD	OS	Quartile	All	0.327	0.801	.003	10	view →
GBM	OS	Tertile	All	0.277	0.538	.022	6	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

CNGA4–CCRCC (DFS)

Open the CCRCC breakdown →