CNGA4

Across TCGA cell cohorts, CNGA4 mutation is significantly associated with the RNA expression of many other genes, with 420 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CNGA4-associated genes across cancer lineages are CALHM4, NPSR1, and KRTAP12-3. Each is linked with CNGA4 in more than 1 cancer types. Because this analysis shows association rather than direction, both CNGA4-to-partner and partner-to-CNGA4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CALHM4 grouped by CNGA4-low versus CNGA4-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CNGA4→partner) and Y-score (partner→CNGA4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	CALHM4 →	+0.019	+5.269	.004	<.001	3	1
BLOOD_Leukemia	NPSR1 →	+0.036	+4.152	<.001	.009	3	1
BLOOD_Leukemia	KRTAP12-3 →	+0.092	+4.539	<.001	.007	3	1
BLOOD_Leukemia	TLE7 →	+0.034	+4.969	<.001	.003	3	1
BLOOD_Lymphoma	CBLL2 →	+0.018	+4.867	<.001	.009	3	1
BLOOD_Lymphoma	SPAG11A →	+0.080	+4.867	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 420 associations by consensus.

CALHM4 by CNGA4 expression — BLOOD_Leukemia

Explore this box plot interactively →