CNGA2

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, CNGA2 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of CNGA2’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where CNGA2 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types CNGA2 is over-expressed in tumor, although a few such as PAAD show the opposite, repressed pattern.

BRCA, KICH, and UCEC are the cancer types where CNGA2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CNGA2 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
BRCAAllII,III,IV+0.256<.0016view →
KICHAllAll+0.088.0053view →
UCECAllAll+0.296.0422view →
PAADFemaleAll−0.035.0192view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

Exploration