Across TCGA patient cohorts, CNGA1 mutation is significantly associated with the total protein of many other genes, with 39 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CNGA1-associated genes across cancer lineages are eIF4E, Notch1, and Rad50. Each is linked with CNGA1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CNGA1-to-partner and partner-to-CNGA1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CNGA1→partner) and Y-score (partner→CNGA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	eIF4E →	+0.191	+2.222	.010	.010	3	2
UCEC	Notch1 →	+0.173	+2.710	.001	.003	3	2
UCEC	Rad50 →	-0.188	-1.678	.043	.023	3	2
UCEC	ATM →	-0.601	-2.584	<.001	.010	3	2
UCEC	Caveolin-1 →	-0.601	-3.321	.031	.009	3	2
UCEC	EGFR_pY1068 →	-0.243	-2.087	.011	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 39 associations by consensus.

Exploration

CNGA1 survival (RNA) · tumor vs normal (RNA) · all CNGA1 data types