CNGA1

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, CNGA1 mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CNGA1-associated genes across cancer lineages are MYOD1, RESP18, and TPSB2. Each is linked with CNGA1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CNGA1-to-partner and partner-to-CNGA1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CNGA1→partner) and Y-score (partner→CNGA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUNG_NSCLC_LUADMYOD1 →+0.057+3.977<.001.00531
LUNG_NSCLC_LUADRESP18 →+0.025+3.947<.001.00431
SKINTPSB2 →+0.399+3.497<.001.00431
SKINMDFIC2 →+0.055+2.977.002.00631
LARGE_INTESTINELY86 →+0.073+3.550<.001.00431
LARGE_INTESTINESLCO1C1 →+0.554+3.772<.001.00331
Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

Exploration