Across TCGA pan-cancer cohorts, CNEP1R1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated CNEP1R1 data layer compared with 25 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher CNEP1R1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated CNEP1R1 expression acts as an unfavorable survival marker, although some lineages such as HNSC and CCRCC show a favorable association.

HNSC, PDAC, and GBM are the cancer types where CNEP1R1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Quartile	All	0.956	0.532	.001	30	view →
PDAC	DFS	Median	II,III,IV	0.314	0.552	.007	15	view →
GBM	DFS	Median	All	0.296	0.442	.013	5	view →
CCRCC	DFS	Quartile	All	1.000	0.518	.033	2	view →
LSCC	DFS	Median	All	0.889	0.724	.046	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

Exploration

Same gene, other analysis: CNEP1R1 tumor-vs-normal RNA expression · all CNEP1R1 data types