Across TCGA pan-cancer cohorts, CNEP1R1 mass-spec protein differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of CNEP1R1’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where CNEP1R1 mass-spec protein is repressed in tumor relative to normal tissue. In most cancer types CNEP1R1 is over-expressed in tumor, although a few such as LSCC and OV show the opposite, repressed pattern.

LSCC, OV, and CCRCC are the cancer types where CNEP1R1 tumor–normal differential expression is most reproducible.

mass-spec protein tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CNEP1R1 mass-spec protein (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LSCC	All	II,III,IV	−0.195	.006	5	view →
OV	All	All	−0.818	.013	2	view →
CCRCC	All	All	+0.251	.033	2	view →
PDAC	All	All	−0.472	.016	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: CNEP1R1 RNA expression & survival · all CNEP1R1 data types