CNDP2

Across TCGA pan-cancer cohorts, CNDP2 mass-spec protein is linked to patient survival in 7 of 34 cancer types, making it a survival-associated CNDP2 data layer compared with 22 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher CNDP2 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated CNDP2 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and UCEC show a favorable association.

COAD, CCRCC, and LSCC are the cancer types where CNDP2 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Quartile	II,III,IV	0.740	1.000	.009	102	view →
CCRCC	DFS	Tertile	II,III,IV	0.928	0.105	.006	27	view →
LSCC	DFS	Quartile	II,III,IV	0.424	0.853	.013	8	view →
UCEC	OS	Median	All	1.000	0.904	.007	6	view →
GBM	DFS	Median	All	0.655	0.837	.004	4	view →
HNSC	OS	Median	III,IV	1.000	0.484	.038	4	view →
PDAC	OS	Quartile	III,IV	0.868	0.259	.008	3	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

CNDP2–COAD (DFS)

Open the COAD breakdown →