CNDP2

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CNDP2 mutation is significantly associated with the RNA expression of many other genes, with 959 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CNDP2-associated genes across cancer lineages are TEKT5, CHAF1B, and SLBP. Each is linked with CNDP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CNDP2-to-partner and partner-to-CNDP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TEKT5 grouped by CNDP2-low versus CNDP2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CNDP2→partner) and Y-score (partner→CNDP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECTEKT5 →-0.326-2.957.003.00132
UCECCHAF1B →+0.649+2.823.001.00132
UCECSLBP →+0.589+2.716.002.00332
UCECCHAF1A →+0.620+3.021.001<.00132
UCECLETM1 →+0.397+2.716.008.00332
UCECNIPA1 →+0.776+2.343<.001.00332
Each partner links to its Q-omics profile. Showing the 6 strongest of 959 associations by consensus.

TEKT5 by CNDP2 expression — UCEC

Box plot of TEKT5 in CNDP2-low vs CNDP2-high samples in UCEC.

Explore this box plot interactively →

Exploration