CNDP2

Across TCGA patient cohorts, CNDP2 mutation is significantly associated with the total protein of many other genes, with 8 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CNDP2-associated genes across cancer lineages are JNK_pT183_Y185, MEK1, and mTOR_pS2448. Each is linked with CNDP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CNDP2-to-partner and partner-to-CNDP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, JNK_pT183_Y185 grouped by CNDP2-low versus CNDP2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CNDP2→partner) and Y-score (partner→CNDP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	JNK_pT183_Y185 →	-0.190	-2.571	.015	.011	3	1
UCEC	MEK1 →	+0.489	+3.169	.004	.018	3	1
UCEC	mTOR_pS2448 →	-0.163	-2.980	.019	.036	2	2
UCEC	Collagen-VI →	-0.189	-2.986	.049	.035	3	1
UCEC	Di-Ras3 →	-0.188	-3.321	.006	.010	3	1
UCEC	eEF2 →	+0.440	+3.000	.008	.036	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

JNK_pT183_Y185 by CNDP2 expression — UCEC

Explore this box plot interactively →