CMYA5

Across TCGA patient cohorts, CMYA5 mutation is significantly associated with the RNA expression of many other genes, with 8,200 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CMYA5-associated genes across cancer lineages are FANCA, ZC3H14, and GRPEL1. Each is linked with CMYA5 in more than 5 cancer types. Because this analysis shows association rather than direction, both CMYA5-to-partner and partner-to-CMYA5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FANCA grouped by CMYA5-low versus CMYA5-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CMYA5→partner) and Y-score (partner→CMYA5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FANCA →	+0.699	+1.736	<.001	<.001	3	5
COAD	ZC3H14 →	+0.302	+1.861	<.001	.004	3	5
UCEC	GRPEL1 →	+0.439	+1.865	<.001	<.001	3	5
UCEC	NCAPG →	+0.700	+1.508	<.001	<.001	3	5
COAD	KIF20A →	+0.587	+2.847	<.001	<.001	3	5
STAD	LDHA →	+0.623	+2.378	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,200 associations by consensus.

FANCA by CMYA5 expression — UCEC

Explore this box plot interactively →