CMYA5

Across TCGA patient cohorts, CMYA5 mutation is significantly associated with the total protein of many other genes, with 104 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CMYA5-associated genes across cancer lineages are c-Kit, PKC-a, and PCNA. Each is linked with CMYA5 in more than 5 cancer types. Because this analysis shows association rather than direction, both CMYA5-to-partner and partner-to-CMYA5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, c-Kit grouped by CMYA5-low versus CMYA5-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CMYA5→partner) and Y-score (partner→CMYA5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	c-Kit →	-0.148	-1.270	.008	.001	3	6
BRCA	PKC-a →	-0.249	-3.584	.002	.003	3	5
COAD	PCNA →	+0.232	+1.597	.005	.040	3	5
COAD	FASN →	+0.578	+2.178	<.001	.001	3	4
LUSC	PKC-delta_pS664 →	-0.153	-2.475	.002	.001	3	4
BLCA	Cyclin-B1 →	+0.528	+2.087	.001	.005	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 104 associations by consensus.

c-Kit by CMYA5 expression — UCEC

Explore this box plot interactively →