CMTR2

Across TCGA pan-cancer cohorts, CMTR2 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated CMTR2 data layer compared with 20 for mass-spec protein and 9 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher CMTR2 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated CMTR2 expression acts as an unfavorable survival marker, although some lineages such as UCEC and HNSC show a favorable association.

UCEC, HNSC, and GBM are the cancer types where CMTR2 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Median	All	0.978	0.845	.012	34	view →
HNSC	DFS	Quartile	II,III,IV	0.775	0.432	.003	31	view →
GBM	OS	Tertile	All	0.651	0.200	.005	11	view →
OV	DFS	Quartile	All	0.382	0.997	.020	8	view →
CCRCC	DFS	Quartile	II,III,IV	1.000	0.758	.023	2	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

CMTR2–UCEC (OS)

Open the UCEC breakdown →