CMTR2

Across TCGA cell cohorts, CMTR2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,155 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CMTR2-associated GO terms across cancer lineages are 7-methylguanosine RNA capping, 7-methylguanosine mRNA capping, and Regulation of organelle assembly. Each is linked with CMTR2 in more than 16 cancer types. Because this analysis shows association rather than direction, both CMTR2-to-partner and partner-to-CMTR2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, 7-methylguanosine RNA capping grouped by CMTR2-low versus CMTR2-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CMTR2→partner) and Y-score (partner→CMTR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	7-methylguanosine RNA capping →	+0.137	+1.011	<.001	<.001	3	17
OVARY	7-methylguanosine mRNA capping →	+0.137	+1.011	<.001	<.001	3	17
UPPER_AERODIGESTIVE_TRACT	Regulation of organelle assembly →	+0.048	+0.941	<.001	.003	3	14
UPPER_AERODIGESTIVE_TRACT	Late viral transcription →	+0.135	+1.102	<.001	<.001	3	13
LUNG_SCLC	Macroautophagy →	+0.047	+0.717	<.001	.002	3	13
UPPER_AERODIGESTIVE_TRACT	Mitotic recombination →	+0.101	+0.979	.008	.002	2	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,155 associations by consensus.

7-methylguanosine RNA capping by CMTR2 expression — OVARY

Explore this box plot interactively →