Across TCGA patient cohorts, CMTM4 protein abundance is significantly associated with the RNA expression of many other genes, with 13,411 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CMTM4-associated genes across cancer lineages are TK2, ZNF19, and GOLM2. Each is linked with CMTM4 in more than 5 cancer types. Because this analysis shows association rather than direction, both CMTM4-to-partner and partner-to-CMTM4 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CMTM4→partner) and Y-score (partner→CMTM4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	TK2 →	+0.552	+0.553	.001	.008	3	6
OV	ZNF19 →	+0.410	+0.647	.001	.002	3	5
BRCA	GOLM2 →	+0.559	+0.556	.003	.004	3	5
LSCC	IKBKE →	-0.825	-0.481	<.001	<.001	3	5
HNSC	CD274 →	-1.649	-0.658	<.001	<.001	3	5
BRCA	IL15RA →	-0.796	-0.720	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,411 associations by consensus.

Exploration

CMTM4 survival (RNA) · tumor vs normal (RNA) · all CMTM4 data types