Across TCGA cell cohorts, CMTM4 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CMTM4-associated genes across cancer lineages are LEUTX, PRAMEF26, and TSHB. Each is linked with CMTM4 in more than 1 cancer types. Because this analysis shows association rather than direction, both CMTM4-to-partner and partner-to-CMTM4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CMTM4→partner) and Y-score (partner→CMTM4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	LEUTX →	+0.226	+5.321	<.001	.005	3	1
CNS	PRAMEF26 →	+0.270	+5.754	.005	.002	3	1
LARGE_INTESTINE	TSHB →	+0.088	+5.415	<.001	.004	3	1
LARGE_INTESTINE	CCER1 →	+0.012	+4.977	<.001	.007	3	1
LARGE_INTESTINE	BTNL2 →	+0.109	+5.415	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Exploration

CMTM4 survival (RNA) · tumor vs normal (RNA) · all CMTM4 data types