CMTM1

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, CMTM1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,523 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CMTM1-associated GO terms across cancer lineages are Negative regulation of DNA-templated transcription initiation, Negative regulation of transcription initiation by RNA polymerase II, and Microtubule polymerization. Each is linked with CMTM1 in more than 14 cancer types. Because this analysis shows association rather than direction, both CMTM1-to-partner and partner-to-CMTM1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of DNA-templated transcription initiation grouped by CMTM1-low versus CMTM1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CMTM1→partner) and Y-score (partner→CMTM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BONENegative regulation of DNA-templated transcription initiation →+0.130+0.969<.001.003315
BONENegative regulation of transcription initiation by RNA polymerase II →+0.130+0.969<.001.003315
LARGE_INTESTINEMicrotubule polymerization →+0.132+1.059<.001<.001315
PANCREASEstablishment of mitotic spindle localization →+0.113+0.963<.001<.001314
BONEProtein polymerization →+0.084+0.965<.001.001314
BONEPositive regulation of cellular response to transforming growth factor beta stimulus →+0.119+1.062.002.001314
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,523 associations by consensus.

Negative regulation of DNA-templated transcription initiation by CMTM1 expression — BONE

Box plot of Negative regulation of DNA-templated transcription initiation in CMTM1-low vs CMTM1-high samples in BONE.

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Exploration