Across TCGA cell cohorts, CMSS1 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible CMSS1-associated genes across cancer lineages are ACER1, FAM187B, and C9orf92. Each is linked with CMSS1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CMSS1-to-partner and partner-to-CMSS1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CMSS1→partner) and Y-score (partner→CMSS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	ACER1 →	+0.105	+3.823	<.001	.006	3	1
SKIN	FAM187B →	+0.044	+3.684	<.001	.006	3	1
SKIN	C9orf92 →	+0.094	+4.347	<.001	.001	3	1
SKIN	OR10G2 →	+0.014	+4.437	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Exploration

CMSS1 survival (RNA) · tumor vs normal (RNA) · all CMSS1 data types